Vigoran

Composition: Each tablet contains:
Sildenafil (Citrate) 50mg.

Properties: Vigoran® (Sildenafil) is rapidly absorbed after oral administration with bioavailability of about 40%. Maximum plasma concentration is reached within 30 -120 minutes (median 60 minutes). It is metabolized predominantly in the liver into an active metabolite.

Both Sildenafil and its major metabolite, N-desmethyl Sildenafil, have terminal half-lives of about 4 hours and both are 96% bound to plasma protein.

Indications: Vigoran® is used in the treatment of erectile dysfunction.

Contra-Indictions: -    Hypersensitivity to Sildenafil.
-    Patients on nitrates therapy.

Adverse Effects:-    In about 2% only of patients: Headache, flushing, dyspepsia, nasal congestion or diarrhea may rarely occur.
-    Abnormal vision: Mild and transient, predominantly color tinge to vision (a bluish tinge or haze to vision) but also increased sensitivity to light or blurred vision.
-    Other adverse effects may occur in less than 2% of patients, which include:

Cardiovascular adverse effects:    Angina pectoris, AV block and syncope.
Digestive adverse effects:    Vomiting, glossitis, stomatitis, rectal and hemorrhage.
Metabolic adverse effects:    Thirst, edema, hypoglycemia and gout.
Respiratory adverse effects:    Dyspnea and bronchitis.
Nervous adverse effects:    Hypertonia, neuralgia and neuropathy.
Urogenital adverse effects:    Cystitis, nocturia, urinary frequency and urinary incontinence.

Dosage & Administration: Dose:
-    One tablet (50mg) of Vigoran® is to be taken one hour before sexual activity. The dose may be increased to a maximum of two tablets (100mg), not more than once per day.
-    Starting with a dose of 25mg should be considered in geriatric, hepatic or renal patients.

How supplied: Packs of one or two strips each of two tablets.

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