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Ketolgin
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Ketolgin
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Composition: SR capsules:Â Â Â Each capsule contains 200mg Ketoprofen in S.R. pellet form. Suppositories:Â Â Each suppository contains 100mg Ketoprofen. Ampoules:Â Â Â Â Â Â Â Each ampoule contains 100mg Ketoprofen. Gel: Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 2.5% Ketoprofen.
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Properties: Ketoprofen (Ketolgin®) is a non-steroidal anti-inflammatory propionic acid derivative. It rapidly relieves pain, reduces fever and decreases inflammation with high tolerability on the gastro-intestinal tract. It is rapidly absorbed with a peak plasma concentration occurring about 0.5 to 2 hours after oral administration. Ketolgin® is also well absorbed from the intramuscular and rectal routes. It could be administered also as an intravenous infusion. Plasma protein binding is 99%. Substantial concentrations are found in synovial fluid. It is metabolized mainly by conjugation with glucuronic acid and is excreted in the urine.
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Indications: -   Painful and inflammatory conditions e.g. headache, dysmenorrhea, dental pain, traumatic pain, post-operatively, gouty pain and soft tissue disorders. -   Rheumatic pain, musculoskeletal and joint disorders e.g. ankylosing spondylitis, osteoarthritis, sciatica and rheumatoid arthritis. Also in peri-articular disorders, such as bursitis and tendinitis -   Febrile conditions e.g. tonsillitis and pharyngitis
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Contra-Indictions: -Â Â Â Patients with known hypersensitivity to the drug. -Â Â Â Active peptic ulcer. -Â Â Â Patients in whom bronchospasm is precipitated by aspirin or other NSAIDs
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Adverse Effects:Mild gastro-intestinal side effects that can be reduced by taking the drug with meals.
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Dosage & Administration: SR capsules:    1 capsule (200 mg) once daily. Suppositories:  1 suppository (100 mg) daily. Ampoules:      1-2 ampoules daily (may be taken at 4 hours interval if necessary) up to a  maximum of 200 mg daily intramuscularly or by intravenous infusion Gel:            Apply 2-4 times daily on the affected area.
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How supplied: SR Capsules: Â Â Â Strips of 10 capsules in packs of 1 strip. Suppositories:Â Â Packs of 5 suppositories. Ampoules: Â Â Â Â Packs of 3 ampoules.
Gel:              Tubes of 15 or 40gm Ketolgin® is also available in a fast acting tablet form 25mg and 50mg
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